Abstract
In today's ever-growing concerns about the coronavirus disease (COVID-19) pandemic, many experience sleep insufficiencies, such as difficulty falling or staying asleep, sleep-related behavioral symptoms, and out-of-phase circadian rhythmicity despite the lack of history of earlier such symptoms. Meanwhile, the disruption in sleep bioparameters is experienced more in people with a history of sleep disorders. The behavioral sleep disorders in the current situations are prevalent given the today's amount of anxiety everyone is feeling about COVID-19. On the other hand, evidences indicated that the cross-link between impaired sleep efficiency and disrupted innate immunity makes people susceptible to viral infections. The present brief review highlights the links between psychosocial stress, sleep insufficiency, and susceptibility to viral infections in relevance to COVID-19 situation. The stress management measures, including addressing sleep-related disorders and sleep hygiene, will have a notable impact by harnessing immune response and thus reducing the susceptibility to viral infections.
Highlights
Sleep health has been addressed as a key pillar for overall health in humans [1,2,3]
We demonstrated in an earlier report that practicing mindfulness exercise and mantra meditation to counteract anxiety could reinforce some humeral immune competency measures [27]
We propose a direct relationship between sleep disorder with viral infection, where if sleep disorder is regulated, a decrease in SARS-CoV-2 related mortality rate may occur
Summary
Sleep health has been addressed as a key pillar for overall health in humans [1,2,3]. Multidisciplinary initiatives encompassing medical, psychobehavioral, and sleep health clinical service provision would need to be considered to further help with today’s burden of the COVID-19 pandemic These are current and future direction studies. The anxietyinduced impairments in immune response was restricted to the cellular immunity (i.e., total number of lymphocytes, granulocytes, monocytes, helper, and cytotoxic T cells, as well as natural killer cells), and humoral immunity measures, such as circulating immunoglobulins A, G, and E [10] Such results have proposed that anxious animal could be more susceptible to infections and inflammation, especially when they were exposed to a chronic state of anxiety [10, 14, 26]. The relation between emotion regulation and immunity needs to be further investigated based on which the effects of mental health treatments either through pharmacotherapy or psychobehavioral approaches on immunity would possibly be better explained in future studies [8, 28]
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