Abstract
Urinary tract infections (UTIs) are one of the most common infections in the United States and consequently are responsible for significant healthcare expenditure. The standard urine culture is the current gold standard for diagnosing urinary tract infections, however there are limitations of the test that directly contribute to increased healthcare costs. As a result, new and innovative techniques have been developed to address the inefficiencies of the current standard—it remains to be seen whether these tests should be performed adjunctly to, or perhaps even replace the urine culture. This review aims to analyze the advantages and disadvantages of the newer and emerging diagnostic techniques such as PCR, expanded quantitative urine culture (EQUC), and next generation sequencing (NGS).
Highlights
Developing Diagnostic Tools forDr Robert Koch was a German microbiologist and Nobel Laureate perhaps best known for his research and discovery of the Tubercle Bacille (TB) bacterium in the late19th century
The standard urine culture is a primary example as it is the current gold standard for diagnosing urinary tract infections (UTI’s), a leading cause of bacterial infections in the United States
These results indicate that candiduria is not adequately identified by standard urine culture methods
Summary
He is often considered one of the “fathers of bacteriology” for propagating the germ theory of disease and developing four basic criteria to demonstrate that disease is caused by a particular organism, which is known as Koch’s postulates. In his 1881 paper “Zurr Untersuchung von Pathogenen Organismen” (On the Examination of Pathogenic Organisms), Koch demonstrates why he is referred to as the “grandfather of cloning,” as he describes a technique to grow isolated colonies of bacteria that would lay the foundation for one of the most commonly used laboratory techniques today: the cell culture [1]. As a result of its high incidence, UTI’s are responsible for $1.6 billion in annual healthcare costs, which represents a clear burden in the national healthcare system [4]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
