Abstract
Atherosclerotic plaque rupture remains the leading cause of acute coronary syndrome (ACS), myocardial infarction and stroke (Lloyd-Jones et al. 2010). Atherosclerotic lesions develop inside the arterial wall. Vulnerable plaque (VP), which is characterised by a relatively large extracellular necrotic core and a thin fibrous cap infiltrated by macrophages, is prone to rupture (Virmani et al. 2000). The rupture of the thin-cap fibroatheroma may lead to the formation of a thrombus, causing the acute syndrome and possibly death (Virmani et al. 2006). The disease remains asymptomatic for a long time, but early detection of vulnerable atherosclerotic lesions is a crucial step in preventing risk of rupture and managing ACS and strokes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Computer Methods in Biomechanics and Biomedical Engineering
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
