Abstract

Stillbirth is the mayor contributor to perinatal mortality. To report a system for classification of fetal deaths. Retrospective cohort study of 29,916 births with 258 fetal deaths that occurred in a public hospital. Data were obtained from audit reports of stillbirths. The method for classification “obstetric condition relevant to the death” was applied, based on obstetric and placental pathological findings analyzed exclusively by a single obstetrician and a single pathologist. Ninety two percent of obstetric conditions causing fetal death were identified. The most commonly reported were ascending bacterial infection in 26%, congenital anomalies in 19%, arterial hypertension in 12% and placental pathology in 12%. Fetal growth restriction was identified in 50% of stillbirths. Ninety percent were secondary to a primary obstetric condition and 10% had an unexplained cause. Placental abruption as the final cause of fetal death was identified in 60% of cases with arterial hypertension, 43% of cases with placental pathology and 37% of ascending infections. Fetal deaths occurred during pregnancy in 82% of cases and during labor in 17%. Intrapartum asphyxia occurred in 0.8% of stillbirths and presented in term pregnancies. The “obstetric condition relevant to the death” method for classification of fetal death is effective to identify the originating obstetric cause of stillbirth and reduces the impact of fetal growth restriction and intrapartum asphyxia as the leading causes of death.

Highlights

  • Stillbirth is the mayor contributor to perinatal mortality

  • Material and Methods: Retrospective cohort study of 29,916 births with 258 fetal deaths that occurred in a public hospital

  • Fetal growth restriction was identified in 50% of stillbirths

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Summary

Background

Stillbirth is the mayor contributor to perinatal mortality. Aim: To report a system for classification of fetal deaths. Que proporciona baja tasa de mortinatos inexplicables, logra disminuir la elevada proporción de casos primarios de mortinatos por RCIU encontrados por ReCoDe, al identificar por los antecedentes obstétricos la condición materna, fetal o placentaria responsable de aquellos[10]. En el HCSBA desarrollamos el método de clasificación de muerte fetal, condición obstétrica relevante de la muerte (CORM), basándonos en los antecedentes obstétricos y biopsia placentaria. El objetivo de este trabajo es presentar un sistema de clasificación de la muerte fetal, que permita mejorar la comprensión de las principales causas y poder evitar mortinatos futuros. Clasificación de las muertes fetales Nuestro sistema de clasificación se basó en métodos propuestos anteriormente[11,12,13] que permitieron desarrollar el sistema CORM (condición obstétrica relevante de la muerte) mediante los antecedentes obstétricos y los hallazgos histopatológicos placentarios. Hipertensión arterial: Preeclampsia, hipertensión arterial crónica, con algunas condiciones clínicas: desprendimiento prematuro de placenta normo inserta (DPPNI), síndrome de HELLP, RCIU, asociado con algunos hallazgos placentarios: infarto vellositario, arteriopatía de vasos deciduales, hematoma retroplacentario, hemorragia intervellositaria, endovasculitis hemorrágicas de vasos fetales, vasculopatía fetal trombótica, trombosis intervellositaria[22,25]

Diabetes
Obesidad
Trombofilia
Drogas
Infección ascendente bacteriana
Infección ascendente micótica
12. Enfermedades virales
13. Infección por Listeria monocytogenes
Alteraciones circulatorias maternas y fetales y RCIU
Findings
Patología del cordón umbilical
Full Text
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