A new feruloyl tyramine glycoside from the roots of Achyranthes bidentata

Abstract

Aim To study the chemical constituents of the roots of Achyranthes bidentata Bl. Methods The chemical constituents were isolated and purified by macroporous adsorptive resin D101, silica gel, and ODS column chromatographies and preparetive HPLC. Their structures were elucidated on the basis of 1D and 2D NMR analyses. Results Two feruloyl tyramine glycosides and seven triterpenoid saponins were obtained and identified as N-trans-feruloyl-3-methoxytyramine-4′- O-β-D-glucopyranoside ( 1), N-trans-feruloyl-3-methoxytyra mine-4- O-β-D-glucopyranoside ( 2), PJS-1 ( 3), chikusetsusaponin IVa ( 4), oleanolic acid 3- O-[β-D-glucuronopy ranoside-6- O-methyl ester]-28- O-β-D-glucopyranoside ( 5), oleanolic acid 3- O-[β-D-glucuronopyran-oside-6- O-ethylester]-28- O-β-D-glucopyranoside ( 6), oleanolic acid 3- O-[β-D-glucuronopyranoside-6- O-butyl ester]-28- O-β-D-glucopyranoside ( 7), ginsenoside R 0 ( 8) and hederagenin-28- O-β-D-glucopyranosyl ester ( 9). Conclusion Compound 1 is a new feruloyl tyramine glycoside, while compounds 2 and 9 are reported from A. bidentata for the first time.