Abstract

A new ferulic acid derivative, (1S)-2-O-Z-feruloyl-1-(4-hydroxyphenyl)ethane-1,2-diol (1), together with five known compounds 2–6, was isolated from the radix of Angelica sinensis. Their structures were elucidated on the basis of spectroscopic data and comparison with literature data. Compounds 1–6 were evaluated for their anticoagulant activities in vitro. The results have shown that all the compounds prolong thrombin time, but had no significant effects in modulating prothrombin time.

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