A new evaluation technique for FIA measurements: projective reference evaluation

Abstract

In this contribution we present a new evaluation technique used for flow injection analysis (FIA) measurements called projective reference evaluation. Using different FIA systems employing an enzyme cartridge in combination with an oxygen electrode for glucose measurement, an enzyme field effect transistor for urea measurement as well as an enzyme optode for penicillin measurement it will be demonstrated, that the new evaluation technique is able to calculate reliable analyte concentrations even from heavily faulty signals. The occurrence of a fault can be detected very easily, using the new technique. Furthermore, it will be shown, that the linear measurement range of a FIA system can be extended significantly. Applying this evaluation technique the whole information of the analysis system inherently hidden in the measurement signal is exploited. The simplicity of the procedure implied its use for on-line application in a process FIA where a reliable evaluation as well as a fast fault detection is imperative.