A New Direction in Understanding the Pathogenesis of Respiratory Syncytial Virus Bronchiolitis: How Real Infants Suffer

Abstract

cine, but a failure to adhere to it may have led to fundamental misunderstandings of the pathogenesis of infant viral lower respiratory tract infections. Viral lower respiratory tract disease, particularly that caused by respiratory syncytial virus (RSV), has long been thought to be the result of an exuberant and aberrant pathogenic immune response. However, a logistically elegant and detailed study of the pathology of fatal infant RSV and influenza infec-