Abstract

Letters21 June 2005A New Concept of Unopposed β-Adrenergic Overstimulation in a Patient with PheochromocytomaVitaly Kantorovich, MD and Karel Pacak, MD, PhD, DScVitaly Kantorovich, MDFrom the National Institutes of Health, Bethesda, MD 20892.Search for more papers by this author and Karel Pacak, MD, PhD, DScFrom the National Institutes of Health, Bethesda, MD 20892.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-142-12_Part_1-200506210-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Background: The concept of unopposed β-adrenergic overstimulation during selective α-adrenergic blockade in patients with pheochromocytoma is well recognized (1-4). We present a case that suggests the existence of an opposite phenomenon: a syndrome of unopposed β-adrenergic overstimulation.Case Report: A 46-year-old woman with multiple endocrine neoplasia type 2A was admitted to the endocrine ward of the National Institutes of Health Warren Grant Magnuson Clinical Center. On a previous admission, she had reported progressive spells of headaches, paleness, and palpitations and was found to have bilateral adrenal pheochromocytomas (right side, 4.7 × 3.1 cm; left side, 2.0 × ...

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