Abstract

On page 1056, researchers report the first possible explanation for how alcohol damages the developing brain. They show that alcohol works through the receptors for two of the brain9s neurotransmitters, glutamate and GABA, to kill brain neurons in rat pups. In addition to carrying an important message for the public about the dangers of alcohol use during pregnancy, the work could provide a first step toward controlling that damage, possibly with drugs that block alcohols9 effects on the receptors.

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