A NEW BREATH FOR MALIGNANT HYPERTENSION

Abstract

Objective: This registry aims to assess modern epidemiology of the disease, diversity of current management and care pathway, to deepen our pathophysiological knowledges, to modernize the definition of this form of hypertension and its diagnostic criteria. The network that will emerge will finally lead to the opportunity of setting up therapeutic trials and establishing recommendations based on solid scientific evidence. Design and method: We will conduct the first prospective multicentric observational cohort about malignant hypertension. We aim to recruit at least 500 patients with a 5 years follow up. Our main objective will be to define their prognosis at 5 years. The impact of the patient's phenotype, type and number of target organs affected will be studied. A modern definition, adapted to these results, could be proposed. The epidemiology of the disease, the care pathways, the target organ disorders and the management carried out in the centers will be described in detail. Results: We recruited more than thirty centers frequently involved in malignant hypertension management. We are ready to start the inclusion. Conclusions: We will conduct the first prospective multicentric observational cohort about malignant hypertension. It should make it possible to deeply increase our knowledges about the disease, and finally to modernize the guidelines on this topic.