Abstract

Five austalide meroterpenoids, including a new one named 13-deoxyaustalide Q acid methyl ester, were isolated from the ethyl acetate extract of the fungus Penicillium sp. SO01. The structure of the new compound was determined on the basis of IR, UV, HR-ESI-MS NMR spectra and CD data. The cytotoxicities of compound 1 against three human tumor cell lines were also tested, with IC50 values of 27.66 μM (SW-1990 cell line), 28.77 μM (Hep3B cell line), and 39.93 μM (HepG2 cell line).

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