A new antibiotic, 1-(p-hydroxyphenyl)-2,3-diisocyano-4-(p-methoxyphenyl)-buta-1,3-diene. II. Elucidation of the structure. (Studies on antiviral and antitumor antibiotics. 3.).

Abstract

In our screening for antiviral antibiotics using the agar diffusion-plaque inhibition method, a new antibiotic was obtained in crystalline form from the filter cake of the fermented broth of Dichotomomyces albus SAITO. The structure of the antibiotic was determined to be l-(p-hydroxyphenyl)-2, 3-diisocyano-4 (p-methoxyphenyl)-buta-l, 3-diene from the interpretation of the ultraviolet absorption, infrared absorption, nuclear magnetic resonance and mass spectra.