A new and green approach for regiospecific synthesis of novel chromeno‐triazolopyrimidin using tungstic acid immobilized MCM‐41 as a reusable catalyst

Abstract

AbstractA novel, eco‐friendly and fast route has been developed for the synthesis of new and known triazolo[1,5‐a]pyrimidin fused chromone derivatives via a one pot three‐component reaction of 3‐amino‐1,2,4‐triazoles, aromatic aldehydes and 4‐hydroxycoumarin in aqueous medium at room temperature. These reactions are catalyzed by MCM‐41‐HWO4 as a safe and recyclable mesoporous solid acid. It combines successfully the synergistic effect of green chemistry with nanocatalysis. The yields are high and the products were characterized by 1H NMR, 13CNMR spectra and elemental analysis.