Abstract

Guillain-Barré syndrome (GBS) is a complicated degenerative disorder. Its etiology is unclear, although it has been associated with both cell and humoral mediated autoimmune mechanisms. The disease causes ascending paralysis and loss of cranial nerve function. Manifestations may be acute or chronic, and temporary or permanent, depending on the degree of neuronal destruction. Because of GBS's pervasive nature, health care is a challenge. Patient care focuses on risks related to ineffective airway clearance and impaired mobility. Psychosocial care and patient education are also integral components of care.

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