Abstract
We hereby demonstrate an intravascular wireless and batteryless microscale stimulator, designed for (1) low power dissipation via intermittent transmission and (2) reduced fixation mechanical burden via deployment to the anterior cardiac vein (ACV, ∼3.8mm in diameter). We introduced a unique coil design circumferentially confined to a 3 mm diameter hollow-cylinder that was driven by a novel transmitter-based control architecture with improved power efficiency. We examined wireless capacity using heterogenous bovine tissue, demonstrating >5V stimulation threshold with up to 20mm transmitter-receiver displacement and 20° of misalignment. Feasibility for human use was validated using Finite Element Method (FEM) simulation of the cardiac cycle, guided by pacer phantom-integrated Magnetic Resonance Images (MRI). This system design thus enabled sufficient wireless power transfer in the face of extensive stimulator miniaturization. Our successful feasibility studies demonstrated the capacity for minimally invasive deployment and low-risk fixation.
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