Abstract

Computer simulations show how low-intensity illumination can be used to terminate cardiac arrhythmias.

Highlights

  • Related research article Hussaini S, Venkatesan V, Biasci V, Romero Sepulveda J, Quinonez Uribe R, Sacconi L, Bub G, Richter C, Krinski V, Parlitz U, Majumder R, Luther S. 2021

  • Cardiomyocytes are excited when a sufficiently strong electric stimulus causes them to depolarize; they remain in their activated state for some time; and, lastly, they return to their resting state, ready to be activated again

  • Cardiac arrhythmias can be caused by various factors – such as diseased cells and scar tissue – and they are associated with serious clinical conditions, including myocardial infarction, heart failure, and sudden cardiac death

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Summary

Introduction

Related research article Hussaini S, Venkatesan V, Biasci V, Romero Sepulveda J, Quinonez Uribe R, Sacconi L, Bub G, Richter C, Krinski V, Parlitz U, Majumder R, Luther S. 2021. Electrical excitation originates from specialized pacemaker cells in the sinus node of the heart, which depolarize automatically. One specific mechanism responsible for cardiac arrhythmia is so-called re-entrant electrical activity: this happens when the electrical impulse that excites cardiomyocytes does not terminate after all cells have been activated.

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