A modified STOP-Bang questionnaire for OSA screening in the young, middle-age women

Abstract

Objective:The STOP-Bang（S-B） questionnaire is widely used for screening patients with OSA. However, BMI and NC cutoff value in the original S-B questionnaire is 35 kg/m²and 40cm, the BMI and NC value in the young and middle-aged female patients in China is lower than that. We aimed to establish a more appropriate modified STOP-Bang（MS-B） questionnaire. Method:A total of 523 cases with suspected OSA in the young and middle-aged female were included in this study. All patients were asked to completed the S-B, MS-B questionnaire and undergo overnight polysomnography（PSG）. The BMI and NC value of the MS-B were determined by the optimal operating points of the ROC. The ability of S-B and MS-B were assessed by ROC and McNemar's test. Result:BMI=28 kg/m²and NC=36 cm as alternative cutoff is to refine S-B questionnaire. When taking apnea hypopnea index（AHI） ≥5 times/h, ≥15 times/h and ≥30 times/h as cut-offs, MS-B had higher sensitivity（88.7% vs 86.7%, 92.8% vs 87.7%, 95.0% vs 90.1%, respectively） and the area under the curve（0.74 vs 0.706, 0.734 vs 0.703, 0.739 vs 0.699, respectively） than S-B. There were significant differences in McNemar test（P<0.05）. Conclusion:This study examined the clinical utility of MS-B. MS-B may improve predictive performance of S-B questionnaire in the young and middle-aged female with OSA.