A Modified Active Brownian Dynamics Model using Asymmetric Energy Conversion and its Application to Cargo Transport by Multi-Motors

Abstract

We consider a modified active Brownian particle model for an application to the cargo transport by multi-motors. In our model each motor has its own energy depot to convert the internal energy into mechanical energy via a non-linear conversion mechanism and is interacting with the cargo harmonically. A different kind of motor is described by a different strength of interaction. By introducing stochastic energy supply to each motor independently and flashing ratchet potential synchronized to the stochastic energy supply, we perform an active Brownian dynamics simulation. Mean velocity, stall force, forward-backward step profiles are investigated for various interaction strengths of the motors with the cargo under the influences of external load, thermal noise, and ATP concentration.