A model-based approach for the quantification of H reflex depression in humans

Abstract

The analysis of the H reflex, a homologue of the stretch reflex, is useful as an aid in understanding certain neurologic disorders as it reflects some aspects of spinal cord neuronal circuitry and dynamics. Here, a dynamical model is used to describe the H reflex depression in humans in response to trains of stimuli. The model describes the interplay of neurotransmitter depletion and replenishment in the presynaptic boutons and has been used to study transmitter turnover in the Ia to motoneuron synapses in the cat.