Abstract

A model is proposed which implies post-transcriptional cleavage of primary transcription products namely heterogeneous nuclear RNA. The stretches to be excised are complementary to other RNA stretches which are coded for by different transcription sequences. Once complementary sequences have hybridized, an endonuclease cuts the molecule at the junction between double-stranded and single-stranded portions. Only single-stranded portions, possibly after RNA ligase iigation, are translated, as mRNA, on polysomes.

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