Abstract
Biomolecular condensates are two- and three-dimensional compartments in eukaryotic cells that concentrate specific collections of proteins and nucleic acids without an encapsulating membrane. Many condensates behave as dynamic liquids, and some are believed to form through liquid-liquid phase separation (LLPS) driven by interactions between multivalent macromolecules. Efforts in my lab have recently expanded in a new direction, to understand whether and how LLPS might regulate the organization of chromatin in the eukaryotic cell nucleus.
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