Abstract
This paper discusses the acceptance and use of Health Information Systems in the context of South African Health Practitioners. The paper argues that ideally, Health Practitioners who adopt HIS are poised to significantly improve their operations and services, and thereby offering patient satisfaction and adequately cover operational costs. Despite the continued investment in information system, there is still limited research and knowledge into what influences or affect the use of the system by health practitioners. The paper addresses the inadequacy of literature in addressing the use of health information system by health practitioners, especially in the context of South Africa. To this point this study sought to explore and explain what affects the use of HIS by individuals.
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