Abstract

Summary<ul>o<li>1.A prosthesis for the atrioventricular heart valves has been designed which tends to imitate the natural mitral valve. The valve is cylindric in shape and is made of smooth polyurethane. The fixation ring is flexible, with Dacron mesh and polyurethane sponge provided for fixation. The sutures are shielded from the blood stream. Chordae tendineae are braided in two strands.</li><li>2.The prosthesis was placed in the mitral area of 10 dogs.</li><li>3.Thrombus formation was found in the implantation site of all six dogs which lived two days or longer, and was largest in the corner between the mural part of the valve and the ventricular wall.</li><li>4.The problems of thrombosis on plastic materials in the heart in general and on mitral prostheses in particular are discussed. At present, the ball valve type seems to be the optimal solution as far as thrombus formation is concerned. The smooth polyurethane tube valve herein described has not been tested in man. It offers the advantage of a flexible ring.</li></ul>

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