Abstract
Cells are biomechanical entities that exert and respond to mechanical forces in addition to biochemical signals. Both types of signals co-regulate processes such as cell differentiation, movement, ...
Highlights
Cells are biomechanical entities that exert and respond to mechanical forces in addition to biochemical signals
The cell model must include relevant mechanical features involved in cell migration and be designed to allow cells to interact with other cells, so as to enable emergent behaviours such as the ones observed during angiogenesis
Numerically obtained cell shapes were in part restricted by the probability distribution of protrusion lengths at creation, and by a regulated number of protrusions per parent node
Summary
Cells are biomechanical entities that exert and respond to mechanical forces in addition to biochemical signals Both types of signals co-regulate processes such as cell differentiation, movement, division. The cell model must include relevant mechanical features involved in cell migration and be designed to allow cells to interact with other cells, so as to enable emergent behaviours such as the ones observed during angiogenesis. This means that our cell model will be developed as an autonomous migrating agent based on mechanical principles. A discrete cellular model is proposed as a first step, to study cell migration on a 2 D environment, including minimal biomechanical ingredients for further developments
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Computer Methods in Biomechanics and Biomedical Engineering
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
