Abstract

Bad breath or halitosis affects a majority of the population from time to time, causing personal discomfort and social embarrassment. Here, we report on a miniaturized, microelectromechanical systems (MEMS)-based, amperometric hydrogen sulfide (H2S) sensor that potentially allows bad breath quantification through a small handheld device. The sensor is designed to detect H2S gas in the order of parts-per-billion (ppb) and has a measured sensitivity of 0.65 nA/ppb with a response time of 21 s. The sensor was found to be selective to NO and NH3 gases, which are normally present in the oral breath of adults. The ppb-level detection capability of the integrated sensor, combined with its relatively fast response and high sensitivity to H2S, makes the sensor potentially applicable for oral breath monitoring.

Highlights

  • Bad breath or oral malodor, affects a majority of the population on a regular basis

  • Halitosis in an adult is classified as “normal” if the concentration is within the range of 80–160 parts-per-billion, “weak” if the concentration is within the range of 160–250 ppb, and “strong” if the concentration is greater than 250 ppb [6,7]

  • The sensor was tested for its hydrogen sulfide (H2 S) gas sensitivity, selectivity to nitric oxide (NO) and NH3, and response time

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Summary

Introduction

Bad breath or oral malodor, affects a majority of the population on a regular basis. The presence of plaque, tongue coating [1], gum diseases [2], exposed necrotic tooth pulp, and healing wounds [3]. Microorganisms present in oral cavities react with organic compounds, releasing sulfur-containing by-products that lead to bad breath. Recent developments in sensor technology have provided measuring instruments with sensitive detection of bad breath. The most successful commercial measuring instrument is the HalimeterTM [5], a standard clinical bench-top instrument used to measure volatile sulfur compounds (VSCs), H2 S gas concentration In this instrument, the user blows into a tube attached to the instrument and a concentration value is presented on a display. To more directly address and counteract personal discomfort, ad-hoc mobile monitoring of bad breath would be highly desired To achieve such monitoring, the sensor element is essential, which requires a small form factor for integration, a fast response time, and ppb-level sensitivity.

Sensor Design and Measurement Method
Sensitivity
S sensor a measured
Output current function of H
Comparison
Response Time
A thorough investigation
Output
Working Electrode Current Drift
Halitosis Measurement Range
Conclusions
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