A mimic peroxidase biosensor based on calcined layered double hydroxide for detection of H 2O 2

Abstract

An enzymeless biosensor was explored from Cu–Mg–Al calcined layered double hydroxide (CLDH) modified electrode in this study. The Cu–Mg–Al CLDH greatly promotes the electron transfer between H 2O 2 and GCE, and it is exemplified toward the non-enzymatic sensing of H 2O 2. The results indicate that the Cu–Mg–Al CLDH exhibits excellent electrocatalytic property, high sensitivity, good reproducibility, long-term stability, and fast amperometric response toward reduction of H 2O 2, thus is promising for the future development of man-made mimics of enzyme in H 2O 2 sensors. This work opens a way to utilize simply Cu–Mg–Al CLDH as an electron mediator to fabricate an efficient H 2O 2 biosensor, which exhibits great potential applications in varieties of simple, robust, and easy-to-make analytical approaches in the future.