A Mild and Metal Free Effective Route for the Synthesis of the Benzofuro[3,2‐c]quinoline Frame Work via Pictet‐Spengler Reaction

Abstract

AbstractWe have reported an effective, metal free, one‐pot methodology for synthesising benzofuro[3,2‐c]quinolines via a Pictet‐Spengler reaction under mild conditions in open air. Our approach has a few advantages over the traditional two‐component synthesis as it is step and atom economic, environmentally benign and a convergent synthetic method. We have discussed here the good substrate scope of this novel methodology.