A Middle-Aged Female with Multiple Brownish Plaques and Nodules: A Case Report of Multiple Cutaneous Reticulohistiocytomas

Karuna Singh Sijapati,Smriti Karki,Sudha Karki

doi:10.3126/njdvl.v16i1.19417

Abstract

Non-Langerhans-Cell histiocytosis spectrum of disorders includes multicentric reticulohistiocytosis (MR) and multiple cutaneous reticulohistiocytomas (MCR), which are very uncommon granulomatous conditions. In reticulohistiocytoma, the most common sites of involvement are extensor surfaces, particularly the hands and forearms and the classical lesions are characterised by firm brown or yellow papules, nodules and plaques. As MCR is a very rare granulomatous condition, we report here a middle-aged female a case of MCR and we highlight the significance of considering reticulohistiocytoma in the differential diagnoses of chronic and persistent brownish plaques or nodules on skin.

Highlights

Non-Langerhans-Cell his ocytosis spectrum of disorders include mul centric re culohis ocytosis (MR) and mul ple cutaneous re culohis ocytomas (MCR), which are very uncommon granulomatous condi ons
In multicentric reticulohistiocytosis (MR), skin lesions occur in associa on with a severe, destruc ve, arthropathy, mucosal involvement and other systemic features
As MCR is a very rare granulomatous condi on, we report here a middle-aged female a case of MCR and we highlight the significance of considering re culohis ocytoma in the differen al diagnoses of persistent and chronic brownish plaques or nodules on skin

Summary

Introduction

Non-Langerhans-Cell his ocytosis spectrum of disorders include mul centric re culohis ocytosis (MR) and mul ple cutaneous re culohis ocytomas (MCR), which are very uncommon granulomatous condi ons. The most common site of involvement are extensor surfaces, par cularly the hands and forearms and the classical lesions are characterised by firm brown or yellow papules, nodules and plaques.[1] In MR, skin lesions occur in associa on with a severe, destruc ve, arthropathy, mucosal involvement and other systemic features. MCR cutaneous lesions are histologically iden cal to MR, developing in the absence of arthri s or other systemic lesions.[2] As MCR is a very rare granulomatous condi on, we report here a middle-aged female a case of MCR and we highlight the significance of considering re culohis ocytoma in the differen al diagnoses of persistent and chronic brownish plaques or nodules on skin. A middle-aged female with multiple brownish plaques and nodules: A case report of multiple cutaneous reticulohistiocytomas.

Discussion

Conclusion