Abstract
This study presents a new micromachine-based cell counting and sorting system capable of multi-wavelength detection for biological applications. Chip-based flow cytometers have been extensively investigated recently. Several unique features have been integrated on this new cell-analysis system. First, a series of new serpentine-shape pneumatic micro-pumps were used to drive sample and sheath flows and generate a hydrodynamic focusing effect. The control of fluids could be achieved with ease by using this approach. Multiple embedded optical fibers were then used to transmit the light source and collect induced fluorescence signals in and out of the chip device. Cells labeled with different fluorescent dyes could be then individually detected by corresponding fibers using lasers with different wavelengths. Finally, three pneumatic micro-valves downstream were used for cell sorting. The developed micro flow cytometer could be used for fast analysis of cell-related bio-medical applications.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
