Abstract
A mechanism for controlling the mixing of highly viscous bio-samples at the micro-liter scale is presented. Existing methods for mixing bio-samples using micro-stirrers or shaking micro-wells are only effective for non-highly-viscous materials. The proposed mechanism mixes monoolein, a highly viscous bio-sample, with water in a micro-device called micro-capsule using a micro-channel and centrifugation. To achieve effective mixing, the design of the micro-capsule along with the micro-channel is presented and so is the hydrodynamic model describing the flow of viscous materials in the micro-channel. The mixing process is analyzed according to the Reynolds number of the bio-samples, which is observed during the experiment using digital images for further analysis. Finally, the new approach is verified by X-ray diffraction experiments, which are used to evaluate the effectiveness of mixing. Experimental results not only validate the proposed method but also determine the flow oscillation time in the micro-channel to achieve the efficient mixing.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
