Abstract

Type 1 diabetes is a chronic disease marked by high blood glucose levels, called hyperglycemia. Diagnosis of diabetes typically requires one or more blood tests. The aim of this paper is to discuss a non-invasive method of type 1 diabetes detection, based on physical activity measurement. We solved a binary classification problem using a variety of computational intelligence methods, including non-linear classification algorithms, which were applied and comparatively assessed. Prediction of disease presence among children and adolescents was evaluated using performance measures, such as accuracy, sensitivity, specificity, precision, the goodness index, and AUC. The most satisfying results were obtained when using the random forest method. The primary parameters in disease detection were weekly step count and the weekly number of vigorous activity minutes. The dependance between the weekly number of steps and the type 1 diabetes presence was established after an insightful analysis of data using classification and clustering algorithms. The findings have shown promising results that type 1 diabetes can be diagnosed using physical activity measurement. This is essential regarding the non-invasiveness and flexibility of the detection method, which can be tested at any time anywhere. The proposed technique can be implemented on a mobile device.

Highlights

  • Diabetes mellitus is a group of metabolic diseases that is characterized by hyperglycemia and results from defects in insulin action, insulin secretion, or both [1]

  • The purpose of this research was to find a relationship between the intensity of physical activity and the presence of type 1 diabetes among children and develop a non-invasive method of type 1 diabetes detection

  • Application of decision tree forests, which included five parameters connected with the intensity of physical activity, enabled the prediction of type 1 diabetes presence among children and adolescents between the ages of six and 18 with a high accuracy of 86.09% and specificity of 84.35%

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Summary

Introduction

Diabetes mellitus is a group of metabolic diseases that is characterized by hyperglycemia and results from defects in insulin action, insulin secretion, or both [1]. Type 1 diabetes causes the patient’s blood glucose to become too high. Patients need daily injections of insulin to keep blood glucose levels under control. It is one of the leading health problems in Poland and Europe, for people of all ages. There are many methods that allow determining the parameters of physical activity with high accuracy. These include all monitors like pedometers and accelerometers that have motion sensors and are worn on the body of the subject to perform various motion measurements, e.g., step count, the duration of physical activity, and its intensity [13]

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