Abstract

Kupper and Meydrech and Myers and Lahoda introduced the mean squared error (MSE) approach to study response surface designs, Duncan and DeGroot derived a criterion for optimality of linear experimental designs based on minimum mean squared error. However, minimization of the MSE of an estimator maxr renuire some knowledge about the unknown parameters. Without such knowledge construction of designs optimal in the sense of MSE may not be possible. In this article a simple method of selecting the levels of regressor variables suitable for estimating some functions of the parameters of a lognormal regression model is developed using a criterion for optimality based on the variance of an estimator. For some special parametric functions, the criterion used here is equivalent to the criterion of minimizing the mean squared error. It is found that the maximum likelihood estimators of a class of parametric functions can be improved substantially (in the sense of MSE) by proper choice of the values of regressor var...

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