Abstract
Lymphoedema, a pathological accumulation of extracellular water (ECW), is a severe post-operative complication. Multifrequency bioimpedance analysis (MFBIA) is a method for the detection of changes in ECW. Our aim is to establish the methodology of MFBIA and to apply it on to group of patients undergoing breast cancer surgery.We measured a control group of 60 women, another group of 5 women with pronounced lymphoedema and a group of 36 patients undergoing breast cancer surgery during a 9-month period after surgery using MFBIA and circumferential measurements for recording volume changes in the upper limb. Different linear extrapolations from 1, 5, 50, 100, 200 kHz were determined to find resistance at 0 Hz for each patient; ratios of R0 were evaluated for non-dominant/dominant and non-operated/operated limbs. Pearson's correlation coefficient was used to compare the correlation between the results and patient characteristics.Extrapolation using 5, 50, 100 kHz had the lowest standard deviation. Within the patients with pronounced lymphoedema, bigger differences were found by MFBIA as compared with circumference measurements. A stronger correlation between limb volumes calculated from circumference measurements with weight and BMI as compared with MFBIA was found. Lymphoedema was found in 14 women in the tested group. The best association between patients' subjective symptoms was with the MFBIA measurement.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
