Abstract

Records, which show pH changes resulting from the introduction of sodium bicarbonate, Sippy A, magnesium trisilicate, magnesium superoxol or a suspension of aluminum hydroxide (Amphojel) under constant conditions, into the stomach of dogs, and those obtained in comparable in vitro experiments are reported and discussed. Aluminum hydroxide suspension caused moderate elevations in pH which persisted up to 5 to 6 hours. Sippy A and magnesium superoxol caused marked pH rises of lesser duration. Sodium bicarbonate caused a moderate pH rise of relatively short duration while magnesium trisilicate, after a sharp rise, causes only a slight elevation of short duration.

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