Abstract
Presented are methods of implanting chronically indwelling electrodes or cannulas into brain of infant rats. Anesthesized pups are restrained in a flexible alginate mold that is placed in the stereotaxic instrument. Details of electrode implant are given. We routinely use these methods to accurately place electrodes into subcortical structures of 3- to 15-day-old pups with less than 2% loss of the implant.
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