Abstract
N- Tert-butyloxycarbonyl groups can be removed from substrates supported on Rink's amide resin by treatment with trimethylsilyl triflate/2,6-lutidine. This methodology was illustrated here with syntheses of several peptides, but it is likely to be used more extensively in solid phase syntheses of small molecule libraries.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.