Abstract

Sensitization and subsequent allergic contact dermatitis due to contact with epoxy resin constitutes a major problem in epoxy workers. In search of ways to protect the skin against exposure to epoxy resin an in vitro method was used to evaluate the efficiency of a series of possible barriers. This method is based upon the determination of the breakthrough time of low molecular weight epoxy resin through a standardized layer of cream or polymer derived from an aerosol spray. Detection of the penetrated epoxy resin in the recipient medium, i. e. a test paper, was carried out by means of the naked eye and interferometric infrared spectroscopy. The method has been applied to a series of creams and aerosol-derived polymer films. Significant differences in breakthrough times were observed, indicating that the method can be used for the comparison of the barrier function of potential protective agents.

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