Abstract
A one-pot synthetic protocol involving 1,3-dipolar cycloaddition/deprotonation/elimination/oxidation for the construction of indolizines has been proposed from easily available pyridine derivatives and γ-bromo-crotonates via a metal-free tandem process. A variety of indolizine derivatives were synthesized under mild conditions. Noteworthy features of this synthetic strategy are short reaction time, using air as oxidant and mild reaction conditions.
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