A meta-analysis on pre-eclampsia and ocular fundus changes associated during pregnancy

Abstract

: Pre-eclampsia is a severe life threatening complications of pregnancy and it is characterized by hypertension and significant amount of protein in urine usually occurring during the second half of pregnancy which is mostly after 20 weeks of pregnancy. A systemic meta analysis was planned to analyze and study the recorded pre-eclampsia cases and their fundus changes associated during pregnancy. This systemic self-study have reviewed the facts which were published earlier to determine the current scenario by vast study of statistics and derivation of facts. Vast meta-analysis were conducted with proper examination of data were made to evaluate with final conclusion.Based on our meta-analysis & systematic evaluation on pre-eclampsia and ocular fundus manifestation during pregnancy we observed, studied and derived into several facts and results. We also inferred that ocular examination in patients with pregnancy induced hypertension should be considered as an important tool of clinical evaluation to asses, predict and diagnose the safety of fetal outcomes and the complication and future risk of mother’s life.We conclude that well-being of both mother and fetus is very crucial during pregnancy. This well-being mostly depends upon the placental circulation. Ophthalmic examination of mother’s fundus could be very important tool to assess the health and well-being of both mother and fetus which might indicate to similar microcirculatory changes in placenta and indirectly to fetal well-being.