A Meta-Analysis of the Prevalence of Peptic Ulcer in Chinese Adults

Abstract

Peptic ulcer is a common digestive system disease, with a high incidence and easy recurrence, complications, and even life-threatening, has a serious impact on the physical and mental health of patients, and the current prevalence of peptic ulcer in Chinese adults is different, has not been paid attention to by clinical doctors. Objective To systematically evaluate the prevalence of peptic ulcer in Chinese adults in order to increase clinical attention. Methods The computer searched Chinese databases (CNKI, VIP, WanFang Data, CBM) and foreign language databases (PubMed, Web of Science, EMbase, The Cochrane Library,) for cross-sectional studies of CHINESE adult PU until January 2022. The included literature was evaluated for quality and data extraction, and statistically analyzed using Stata 15.0 software. Results A total of 8 studies, including 29573 participants, were included. Meta-analysis shows that the overall prevalence of peptic ulcer in Chinese adults is 9% [95% CI (6%-11%)]. Subgroup analysis showed that the prevalence of gastric ulcers was 10.0% (95% CI (7%, 13.0%)] in men and 5% (95% CI (3%, 6%)] in women by sex; the prevalence of gastric ulcers was 8.0% (95% CI (2%, 18.0%)] in terms of location, 13% (95% CI (8%, 19%), and in terms of regional distribution, the prevalence of southern ulcers was 9.0% (95% CI (5.0%, 12.0%). , northern region prevalence 9.0% [95% CI (2.0%, 17.0%)]; In terms of age distribution, the prevalence of age ≥61 years, 51-60 years, 41-50 years, 31-40 years, and ≤30 years was 4.0% [95% CI (0%, 7.0%)], 9.0% [95% CI (0%, 19.0%)], 8.0% [95% CI (1.0%, 15.0%)] and 7.0% [95% CI (2.0%, 13.0%)] and 25.0% [95% CI (16.0%, 34.0%)] In terms of occupational types, the prevalence of soldiers, students, workers, and peasants was 1.0% [95% CI (1.0%, 2.0%)], 29.0% [95% CI (24.0%, 33.0%)], 18.0% [95% CI (7.0%, 28.0%)] and 4.0% [95% CI (1.0%, 7.0%)], respectively; in terms of survey time, the prevalence rate before 2000 was 15.0% [95% CI (4.0%, 26.0%)] , prevalence after 2000 was 5.0% [95% CI (3.0%, 7.0%)]; Conclusion The prevalence of PU in adults in China is high, and there are differences in the prevalence of different genders, occupations and regions. Although there is a gradual downward trend, it is easy to recur and has many complications, so it is still necessary to be vigilant.