A Meta-Analysis of the Effect on Myopia Progression Control for Children and Adolescents in Korea

Abstract

Purpose : The purpose of this study was to provide a clinical implication for myopia progression control by synthesizing, comparing and analyzing the studies that have been accumulated effects on myopia progression control of children and adolescents in Korea. Methods : This study collected studies in which myopia progression control was investigated as interventions such as ‘atropine’, ‘orthokeratology lens’, and ‘myopia control lens’ for children and adolescents in Korea. For systematic meta-analysis, 11 studies were finally selected after literature search based on the PICO criteria. It was to be evaluated qualitatively using the tools RoBANS, and metaANOVA was performed to calculate effect size of individual studies and to verify the difference in effect size. Results : The meta-analysis showed that myopia progression control had an effect size, with a total effect size of –0.41 D. As a result of the sub-analysis effect size for myopia progression control, ‘orthokeratology lens’ -0.50 D and ‘myopia control lens’ -0.37 D were shown and significant differences between them were found. The control of myopia progression control was confirmed, which was ‘atropine’ -0.32 D, showing that no significant difference was found. MetaANOVA for myopia progression control showed no difference between the methods. Conclusion : There is no significant difference between the methods to control myopia progression, but it would be necessary to choose a method that has no side effects and to last for a long time.