Abstract
ObjectiveTo evaluate the efficacy and safety of robot-assisted laparoscopic radical prostatectomy (RALP) and laparoscopic radical prostatectomy (LRP) for the treatment of localized prostate cancer.MethodsMeta-analysis was applied using Review Manager V5.3 software and the retrieved clinical trials comparing RALP with LRP for the treatment of localized prostate cancer published from 2000 to 2018 in PubMed, Ovid, ScienceDirect, and EMBASE datasets were analyzed.ResultsThis meta-analysis included 16 articles, totaling 7952 patients, with 5170 RALP patients and 2782 LRP patients. Meta-analysis showed that RALP postoperative complications were fewer (P=0.0007), and the postoperative urinary continence rate was better at 1 year after surgery (P<0.00001). There was no statistical significance between RALP and LRP with regards to the positive incidence of surgical margin (P = 0.18).ConclusionAs an emerging technology, RALP is superior to LRP for localized prostate cancer treatment in terms of postoperative complications, and postoperative urinary continence rate.
Highlights
(1) The patients that were diagnosed with localized prostate cancer treated for the first time, and all had indications for treatment by radical prostatectomy
The meta-analysis demonstrated that patients with radical prostatectomy (RALP) had significantly lower postoperative urinary continence rates 1 year after surgery compared with laparoscopic radical prostatectomy (LRP) (OR=2.09; 95% CI, [1.61, 2.73])
Due to the limited number of published studies and data values, this study analyzed the incidence of postoperative complications in general, and the results showed that robot-assisted laparoscopy was lower
Summary
We conducted a search of PubMed, Ovid, ScineceDirect, and EMBASE from 2005 to 2018. We developed a search strategy as outlined by the Cochrane Collaboration Workbook. The medical subject heading terms and keywords included “prostate cancer prostatectomy”, “radical prostatectomy laparoscopy”, “assisted-laparoscopic”. Prostate cancer is one of the most common malignant tumors in older men [1]. 2.2 Inclusion criteria (1) The patients that were diagnosed with localized prostate cancer treated for the first time, and all had indications for treatment by radical prostatectomy. The literature involved at least one of the following seven indicators: operation time, intraoperative blood loss, blood transfusion rate, surgical margin positive rate and hospitalization time, postoperative urinary function and postoperative complications, and follow-up time more than 1 year
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
