Abstract
Introduction A systematic review of all trials (two Australian and one European) randomizing patients in the prehospital setting to a little or a lot of chest compressions prior to first analysis demonstrated no significant benefit for any patient and for a comparison across subgroups based on initial shockable rhythm and an Emergency Medical Services (EMS) response time interval of >5 min versus ≤5 min. The European trial had suggested a significant difference in this comparison which was not supported in the meta-analysis. A large randomized trial from the Resuscitation Outcomes Consortium (ROC) investigators was completed and published after this systematic review and reported a nonsignificant comparison across a different time interval (4 min) which did not allow a direct comparison. The objective of this study was to obtain unpublished data from the recent trial and expand the meta-analysis.
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