Abstract
Adherence to a Mediterranean lifestyle may be a useful primary and secondary prevention strategy for chronic kidney disease (CKD). This cross-sectional study aimed to explore adherence to a Mediterranean lifestyle and its association with cardiometabolic markers and kidney function in 99 people aged 73⋅2 ± 10⋅5 years with non-dialysis dependant CKD (stages 3-5) at a single Australian centre. Adherence was assessed using an a priori index, the Mediterranean Lifestyle (MEDLIFE) index. Cardiometabolic markers (total cholesterol, LDL-cholesterol, HbA1c and random blood glucose) and kidney function (estimated GFR) were sourced from medical records and blood pressure measured upon recruitment. Overall, adherence to a Mediterranean lifestyle was moderate to low with an average MEDLIFE index score of 11⋅33 ± 3⋅31. Adherence to a Mediterranean lifestyle was associated with employment (r 0⋅30, P = 0⋅004). Mediterranean dietary habits were associated with cardiometabolic markers, such as limiting sugar in beverages was associated with lower diastolic blood pressure (r 0⋅32, P = 0⋅002), eating in moderation with favourable random blood glucose (r 0⋅21, P = 0⋅043), having more than two snack foods per week with HbA1c (r 0⋅29, P = 0⋅037) and LDL-cholesterol (r 0⋅41, P = 0⋅002). Interestingly, eating in company was associated with a lower frequency of depression (χ2 5⋅975, P = 0⋅015). To conclude, Mediterranean dietary habits were favourably associated with cardiometabolic markers and management of some comorbidities in this group of people with non-dialysis dependent CKD.
Highlights
Chronic kidney disease (CKD) affects 9⋅1 % of the population worldwide, placing substantial burden on healthcare systems[1,2]
Significant differences were found between systolic blood pressure and a diagnosis of hypertension and/or cancer between those with early CKD compared with advanced CKD
No significant differences were found for cardiometabolic markers or kidney function between groups according to the median Mediterranean Lifestyle (MEDLIFE) index score
Summary
Chronic kidney disease (CKD) affects 9⋅1 % of the population worldwide, placing substantial burden on healthcare systems[1,2]. Is low diet quality detrimental to CKD, it can result in poor management of underlying comorbidities like cardiovascular disease, diabetes mellitus and hypertension which can further progress CKD[3,4]. For these reasons, there is potential for healthful dietary patterns, like the Mediterranean diet, to aid in the prevention and management of CKD[5]. In a multi-centre trial, a Mediterranean diet supplemented with extra-virgin olive oil or nuts was associated with a 31 % lower incidence of major cardiovascular events in people at high cardiovascular risk[8]. A recent prospective cohort study among journals.cambridge.org/jns
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
