A Medicated Wafers as a Novel Drug Delivery Carrier

Abstract

Throughout the globe, pharmaceutical researchers seek to investigate medicated wafers as a novel instrument for drug delivery. As an alternative strategy to standard dosage forms, medicated wafers have been recognized. Wafers are regarded as convenient for swallowing, self-administering, and rapid dissolving dosage form, making it a versatile drug delivery platform. This delivery system was used through several paths such as oral, buccal, sublingual, and transdermal routes for both systemic and local intervention. The development of effective thin wafers needs an extensive understanding of the pharmacological and pharmaceutical properties of drugs and polymers together with a suitable choice of production procedures. The objective of this review is therefore to provide an overview of the new innovative formulation techniques, the various patents registered, the application in the pharmaceutical field, factors affecting the formulation of thin wafers, including the physicochemical properties of polymers and drugs, anatomical and physiological constraints, and the characterization of wafers. It also includes the latest trends and perspectives for designing thin wafers products and issues for different businesses developing thin wafers.