Abstract

A mathematical model to eliminate malaria by breaking the life cycle of anopheles mosquito using copepods at larva stage and tadpoles at pupa stage was derived aimed at eradicating anopheles pupa mosquito by introduction of natural enemies “copepods and tadpoles” (an organism that eats up mosquito at larva and pupa stage respectively). The model equations were derived using the model parameters and variables. The stability analysis of the free equilibrium states was analyzed using equilibrium points of Beltrami and Diekmann’s conditions for stability analysis of steady state. We observed that the model free equilibrium state is stable which implies that the equilibrium point or steady state is stable and the stability of the model means, there will not be anopheles adult mosquito in our society for malaria transmission. The ideas of Beltrami’s and Diekmann conditions revealed that the determinant and trace of the Jacobian matrix were greater than zero and less than zero respectively implying that the model disease free equilibrium state is stable. Hence, the number of larva that transforms to pupa is almost zero while the pupa that develop to adult is zero meaning the life-cycle is broken at the larva and pupa stages with the introduction of natural enemy. Maple was used for the symbolic and numerical solutions.

Highlights

  • Malaria is one of the high priority tropical diseases in the sub-Saharan Africa in general and Nigeria in particular

  • A mathematical model to eliminate malaria by breaking the life cycle of anopheles mosquito using copepods at larva stage and tadpoles at pupa stage was derived aimed at eradicating anopheles pupa mosquito by introduction of natural enemies ―copepods and tadpoles‖

  • We would establish the stability of the Model free equilibrium (MFE) state by considering the model parameters and using the model equations

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Summary

Introduction

Malaria is one of the high priority tropical diseases in the sub-Saharan Africa in general and Nigeria in particular. There has been many efforts to eradicate malaria from the world over a long period of time, yet it remains a complex disease. It affects human health and continues to be one of the most serious vector borne diseases worldwide. An endemic disease is transmitted through three possible media namely, malaria parasite, human host and anopheles mosquito. The female Anopheles mosquito feeds on human blood. This has resulted to the death of over two million people yearly in the Sub Saharan Africa, with one third of the victims as children in Nigeria

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