Abstract
A simple mathematical model of first and second degree heart block is developed on the assumption that eachR wave, with its associated ventricular contraction, results in the release of a substance which raises the excitation threshold of the conducting tissue lying between theS-A andA-V nodes. The conduction pathway is represented by a chain of excitatory elements, the first member of which is acted upon by a regularly occurringP wave. The rate constant of the removal of this inhibitory substance, i.e., recovery rate, is the only constant necessary to be varied in order to pass from normal to first degree block to second degree.
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