A mathematical analysis of the effects of control strategies on the transmission dynamics of Chlamydiosis

Abstract

Chlamydiosis remains a major public health concern in both developed and developing countries due to its effects on the human reproductive system. While limited modeling studies have been conducted on the transmission dynamics of the disease, none of them have examined the impacts of the combination of environmental hygiene and other control strategies. In this paper, we present a mathematical model to investigate the impacts of public health education, vaccination of susceptible individuals, treatment of symptomatic infected individuals, and environmental hygiene. The basic reproduction number is computed using the next-generation operator and is employed in the stability analysis of equilibrium points. We also perform a sensitivity analysis of the model using a normalized forward sensitivity index to identify the parameters significantly affecting the effective reproduction number. Findings from analytical solutions and numerical simulations demonstrate that, public health education, vaccination, treatment, and environmental hygiene significantly reduce chlamydiosis incidence and prevalence in the population. Consequently, the study recommends implementing these control measures, particularly in regions where the disease is endemic. Thus, findings from this study could be utilized to support decision-making in Chlamydiosis control strategies.