Abstract

Sjogren syndrome is a chronic autoimmune disorder with lymphocytic infiltration of exocrine glands causing oral and ocular dryness and well recognized systemic manifestations. Although primary Sjogren syndrome (pSS) is common in women, it is not well recognized in men. This is the first reported case of pSS in a Sri Lankan male to the best of our knowledge. A 58-year-old man presented with polyuria. He has had sicca symptoms for six months and polyuria was secondary to the increased water intake to relieve oral dryness. Examination revealed enlarged tender bilateral salivary glands. After excluding secondary causes, he was diagnosed with pSS. The treatment commenced with steroids, azathioprine, and symptomatic therapy. Primary Sjogren syndrome is an overlooked diagnosis, especially in men, leading to increased morbidity given its multi-organ involvement. Recognition and supportive therapy can help to improve the quality of life of patients.

Highlights

  • Sjögren syndrome (SS) is an autoimmune disorder and it has the highest prevalence in females among all rheumatological conditions

  • We report a male patient diagnosed with primary Sjögren syndrome and negative anti-Ro/La antibody contrary to the common serological pattern seen in males

  • A 58-year-old man was admitted for evaluation of polyuria and polydipsia for six months

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Summary

Anuradhapura Medical Journal

Sjögren syndrome (SS) is an autoimmune disorder and it has the highest prevalence in females among all rheumatological conditions. We report a male patient diagnosed with primary Sjögren syndrome (pSS) and negative anti-Ro/La antibody contrary to the common serological pattern seen in males

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